Mobile Corona Diagnostic Laboratory for Pandemic Response

    Extensive testing allows to effectively control the pandemic.

    23

    South Korea

    17

    Germany

    corona diagnoses per 100.000 citizens and day

    1%

    32%

    South Korea

    Germany

    positive corona diagnoses daily increase 19.03.20

    Our Bio.Kitchen Mobile Lab covers all processes for COVID-19 detection and safe sample handling

    Micro.bio

    Safely isolate, extract and detect
    coronaviruses using a mobile
    glovebox and autoclave to sterilize
    contaminated materials. Micro.Bio
    provides six open source RT-qPCR
    systems.

    Lab.bio

    The station provides a centrifuge,
    pipettes and a fridge and freezer to
    keep your reagents fresh. The
    convenient storage of consumables
    and the safe transportation of
    chemicals make it the ideal mobile
    lab platform for any environment.

    Syn.bio (optional)

    Syn.Bio adds the Kilobaser and
    Nanopore technologies for DNA
    synthesis (primer printing) and
    sequencing and comes with a
    computer to read and upload your
    corona genomic DNA and download
    latest primers for your locals mutant
    strains.

    Allowing Airport Passenger Testing

    Our Bio.Kitchen Mobile Corona Diagnostic Lab is a ruggedized lab-in-a-box for pandemic response

    • 3 mobile lab stations: Lab.bio (2 units), Micro.bio, Syn.bio (optional)

    • Easily transported and operation - ready to use within ~24h, anywhere in EU

    • Compatible to our molecular and microbiological lab tools

    • Optimized equipment storage compatible with Eurocontainers

    • Extendable table top area to a maximum of 7.2 m² (5 work spaces)

    • On demand: mobile energy generator and voltage regulators

    Bio.Kitchen Mobile Lab Properties

    Durable and Secure

    • Steel frame 25x25x2 mm welded and powder-coated

    • TRESPA® Toplab Plus® 20 mm lab grade tabletop

    • Lightweight, cleanable and robust eloxed aluminium AlucoBond base cabinets

    Practical

    • All machines can be stored in “euro containers” fitted into base cabinets

    • Table addons such as garbage bins, hand soap holders, power-plugs, lights and hygienic paper dispensers available

    • Each stations tabletops can be extended by 850x700mm extensions

    Mobile

    • Each station can be lifted into a transporter or up the stairs by two people

    • Using its robust wheels a station can be positioned anywhere e.g. a wheelchair can access

    Rapid and scalable production
    First mobile lab prototype by late April 2020
    Production ready to scale from May 2020 on

    With 1 station per 100 000 citizens our mobile lab allows to screen up to 70% of the population within 1 year.

    Maximum Capacity:

    190 diagnoses per station per 24h

    Assumptions:
    ● Staffing: 1 clinical laboratory technician at a time working in shifts
    ● qPCRs: 6 RT-qPCR devices, each 16 wells
    ● Test procedure: Per patient 2 swabs (nose+mouth) with 2 PCR reactions + 2 controls are tested
    ● Cycle Time: 90 mins to result per run
    ● Runtime: 6 machines*2 patients * 24h/1.5h= 192 diagnoses/24h, rounded down

    Mobile Corona Laboratory with Instrumentation

    Micro.Bio station

    • Glovebox

    • Autoclave

    • Consumable storage

    • Tap & Sink

      This station is designed to complement Lab.Bio.

    Lab.Bio station

    • Fridge

    • Freezer

    • Waste system

    • Consumable storage

    • Hand-hygiene system

    90.000 €*

    6x open qPCR system

    120.000 €*

    Mobile Corona Laboratories
    are compatible with any
    COVID-19 analytic system of
    your choice. Contact us for
    120.000 €* more information.

    Syn.Bio station

    • DNA concentration
      analysis

    • Kilobaser DNA
      Synthesis

    • MinION DNA
      Sequencer

    • optional pipette sets

    • optional centrifuge

      This station is an optional
      addon and designed to
      complement Lab.Bio and Micro.Bio stations.

    on request

    Laboratory
    Planning

    The offer includes the conception and planning, documentation and purchasing of the equipment (devices and consumables), pre-assembly of all components to the operational stations and a 1-day online introductory to the products and the technical equipment.

    *excl. shipping & VAT. The price is a unbinding offer per unit and may be subject to change. An individual offer is available on request. Our production is scalable up to 50 units per month

    Idea: DNA sequencing and synthesis - teleporting coronavirus diagnostic reagents

    Coronavirus quick tests have to be provided as point-of-care personalised diagnostics. Using our Syn.Bio station, coronaviruses can be sequenced, their genome data sent over the internet and their DNA snippets printed again by a receiving Syn.Bio station in a different location. The printed corona DNA can be tested against patient samples in a clinic within 2h using our open QPCR. Thus, a programmable biological diagnostic reagent can be literally “teleported”. Patients anywhere on the planet can be diagnosed with personalised medicine in real time.

    Target audience:

    healthcare companies, hospitals, industry fairs

     

    Duration:  

    1 day preparation & 2 days experiment

     

    Stations required:  

    Lab.bio, Micro.bio Syn.bio

    RNA Extraction &

    PCR Amplification

    of a patient sample

    DNA Quantification & 
    MinION Sequencing

    Uploading to public databases

    Printing Primers for specific qPCR

    run qPCR on patient samples

    run qPCR on patient samples

    Future: A Mobile Lab can enable resource-limited locations with high-tech solutions sustainably.

    All our Bio.kitchen mobile lab stations can be used as a technological support infrastructure in any place with the need for a laboratory. We envision their usage in resource limited locations for the following purposes:
     

    • Emergency response, e.g. for molecular infection diagnostics in epidemic outbreak situations

    • Complementary to mobile temporary drive thru test sites

    • Flexible high tech upgrade solution for resource limited laboratories

    • Enabling personalised and precision medicine on-site, e.g. COVID-19 Diagnostics  in pop up hospitals

    • Educational infrastructure for microbiology, synthetic biology and microfluidics, e.g. in universities and schools

    Current low-tech reality: Immanuel Nnadi’s Phage Therapy laboratory in Bokkos, Nigeria

    Target users:   Resource-limited hospitals, Universities, NGOs, Governments, Emergency Response Units
     

    Stations required:   Lab.bio, Micro.bio, Syn.bio

    Contact

    Email: trojok[at]unternehmertum.de

    UnternehmerTUM GmbH
    Lichtenbergstr. 6
    85748 Garching bei München

    © 2018 UnternehmerTUM GmbH